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“中风预防:当前的挑战和多模态影像解决方案”学术报告

日期: 2017-04-26    |    阅读(859)

题  目:  Stroke Prevention: Current Challenge and Multi Modality Imaging-based Solution (中风预防:当前的挑战和多模态影像解决方案)
报告人:  Dr Zhongzhao Teng (滕忠照博士) ,英国剑桥大学放射系
时  间:  14:30-15:30 AM (27April 2017, Thursday)
地  点:  生命学馆B619房间
Abstract:
According to the Global Status Report on noncommunicable diseases 2014, World Health Organization (WHO), stoke is the leading cause of deaths in the world (6.7 million per year) and the first cause of disability. It is more severe in China according to the recent Report on Cardiovascular Diseases in China 2014 (7 million stroke survivals and annually 2.5 million first stroke patients in China). Considering the large population suffering from hypertension (270 million) and diabetic (90 million), which are the two main high risk associated with stroke, China is facing a tremendous challenge in stroke prevention.
It has been shown that carotid atherosclerotic diseases is responsible for about 25%-35% of ischaemic cerebrovascular events. In a population-based study with 5 million participants, 1/3 with age over 40 years old had detectable carotid intima thickening. Degree of luminal stenosis is the only validated criterion in current clinical practice. This criterion has been shown to have a serious limitation in assessing the risk of recurrent ischaemic events in the symptomatic cohort and it cannot identify the right individuals in the asymptomatic cohort. It is, therefore, an urgent need to find novel biomarkers.
Studies in the past 20 years have shown that atherosclerotic plaque is a multi-component structure and its morphological and compositional features have a closer relationship with patient clinical presentations and subsequent ischaemic events. However, these features have a low predicting power, in particular, for the asymptomatic cohort. An integrative approach with the combination of local and global features is needed in order to identify the right patient at the right time and provide the right treatment.
About the speaker:
滕忠照博士1994年考入上海复旦大学力学与工程科学系就读本科;于2003年在复旦大学获得博士学位,专业方向是生物流体力学;滕博士于2014年获得剑桥大学博士学位,专业方向是放射学。滕博士目前是剑桥大学放射系生物医学工程研究组负责人。滕博士已发表近100篇经过同行评议的学术论文,并分别获得2016年度剑桥大学和中英创新大赛总冠军,并入选MassChallenge欧洲创新加速计划。
在滕博士的带领下,研究小组研发了基于磁共振成像技术和力学分析的、新颖的多模态血管影像技术。通过结合病灶(如动脉粥样斑块和动脉瘤)的形态、内部组分结构、炎症水平、和力学分析,评价血管粥样斑块和动脉瘤的稳定性。该技术的有效性已经得到在剑桥大学附属医院开展的多个临床研究的验证。
校内合作人: 徐礼胜, Email:  xuls@bmie.neu.edu.cn , Tel:  024-83683200
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